CROI 2026 - CROI 2026

Themed Discussion: Mechanisms and Modifiers: Treatable Causes of Cognitive Impairment and Depression

"Session Overview" by Leah H. Rubin The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Themed Discussion: Mechanisms and Modifiers: Treatable Causes of Cognitive Impairment and Depression

"MASH and the Progression of Cognitive Decline in Older People With HIV: A Prospective Study" by Katekarn Porkaew Chulalongkorn University, Bangkok, Thailand

Themed Discussion: Mechanisms and Modifiers: Treatable Causes of Cognitive Impairment and Depression

"Metabolic Syndrome and Cognitive Impairment Among Men With and Without HIV" by Sara M. Hockney Northwestern University, Chicago, IL, USA

Themed Discussion: Mechanisms and Modifiers: Treatable Causes of Cognitive Impairment and Depression

"Modifiable Factors Could Mitigate Greater Burden of Brain Small Vessel Injury in Female Individuals" by Elana Farrell University of California San Francisco, San Francisco, CA, USA

Themed Discussion: Mechanisms and Modifiers: Treatable Causes of Cognitive Impairment and Depression

"The Impact of Semaglutide on Depressive Symptoms Among People With HIV" by Lara Haidar University of Manitoba, Winnipeg, Canada

Themed Discussion: Mechanisms and Modifiers: Treatable Causes of Cognitive Impairment and Depression

"Discussion With Audience Questions and Answers" by

Themed Discussion: New Host Factors: Regulating Nuclear Events of HIV Replication

"Session Overview" by Edward Campbell Loyola University Chicago, Chicago, IL, USA

Themed Discussion: New Host Factors: Regulating Nuclear Events of HIV Replication

"BLM Helicase Is Required for Efficient HIV Infection in Macrophages" by Andrew Leal Boston University, Boston, MA, USA

Themed Discussion: New Host Factors: Regulating Nuclear Events of HIV Replication

"CD46 Interacts With Sp1 to Control HIV Expression in Infected T Cells" by Pavitra Ramdas National Institute of Allergy and Infectious Diseases, Baltimore, MD, USA

Themed Discussion: New Host Factors: Regulating Nuclear Events of HIV Replication

"Exploring the Role of FUBP1 in HIV Replication and Latency" by Fiona Carter-Tod Northwestern University, Chicago, IL, USA

Themed Discussion: New Host Factors: Regulating Nuclear Events of HIV Replication

"Cis- and Trans-Acting Factors That Mediate Nuclear Retention of Intron-Containing HIV-1 Transcripts" by Anthony Boateng Washington University in St Louis, St Louis, MO, USA

Themed Discussion: New Host Factors: Regulating Nuclear Events of HIV Replication

"Discussion With Audience Questions and Answers" by

Themed Discussion: Noncanonical Mutations Conferring Resistance to InSTIs

"Session Overview" by Daniel R. Kuritzkes Harvard Medical School, Boston, MA, USA

Themed Discussion: Noncanonical Mutations Conferring Resistance to InSTIs

"Env Mutations Are a Gateway for Acquisition of InSTI Resistance" by Yuta Hikichi National Cancer Institute at Frederick, Frederick, MD, USA

Themed Discussion: Noncanonical Mutations Conferring Resistance to InSTIs

"Nucleocapsid Mutations During Virologic Failure of an Integrase Inhibitor-Based Regimen" by Charlotte Charpentier Assistance Publique – Hôpitaux de Paris, Paris, France

Themed Discussion: Noncanonical Mutations Conferring Resistance to InSTIs

"Noncanonical Resistance Mutations in TLD-Treated Individuals With Unexplained Virologic Failure" by Nicola Coetzee Stellenbosch University, Cape Town, South Africa

Themed Discussion: Noncanonical Mutations Conferring Resistance to InSTIs

"Characterization of Mutations Outside the Integrase in HIV-1 Individuals in Whom Dolutegravir Failed" by Aurelie Minelle Kengni Ngueko Centre International de Référence Chantal Biya, Yaoundé, Cameroon

Themed Discussion: Noncanonical Mutations Conferring Resistance to InSTIs

"Discussion With Audience Questions and Answers" by

Themed Discussion: Sleepless in Denver: Impact of Funding Changes on HIV Care

"Session Overview" by Jennifer Kates Kaiser Family Foundation, Washington, DC, USA

Themed Discussion: Sleepless in Denver: Impact of Funding Changes on HIV Care

"Impact of US Funding Shifts on HIV Care: A Rapid Survey of Clinics and Programs in 32 Countries" by Ellen Brazier Institute for Implementation Science in Population Health, New York, NY, USA

Themed Discussion: Sleepless in Denver: Impact of Funding Changes on HIV Care

"Population-Representative Consequences of Foreign Aid Instability for HIV Services in South Africa" by Lindsey Filiatreau Washington University in St Louis, St Louis, MO, USA

Themed Discussion: Sleepless in Denver: Impact of Funding Changes on HIV Care

"Short-Term Poverty Relief and ART Adherence: Insights From a Natural Experiment of SNAP Recipients" by Aaron Richterman University of Pennsylvania, Philadelphia, PA, USA

Themed Discussion: Sleepless in Denver: Impact of Funding Changes on HIV Care

"Discussion With Audience Questions and Answers" by

Themed Discussion: Extra Large Challenges in Steatotic Liver Disease

"Session Overview" by Mark Sulkowski The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Themed Discussion: Extra Large Challenges in Steatotic Liver Disease

"Simple Adiposity Measures Identify MASLD in People With HIV: Results From a US Multicenter Cohort" by Kara Wegermann Duke University School of Medicine, Durham, NC, USA

Themed Discussion: Extra Large Challenges in Steatotic Liver Disease

"Performance of Prediction Scores for Steatotic Liver Disease in Thai PWH on InSTI-Based ART" by Napon Hiranburana HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand

Themed Discussion: Extra Large Challenges in Steatotic Liver Disease

"Effect of DTG/3TC vs BIC/FTC/TAF on Steatotic Liver Disease: 96-Week Analysis of PASO-DOBLE Trial" by Juan Macias University of Sevilla, Sevilla, Spain

Themed Discussion: Extra Large Challenges in Steatotic Liver Disease

"Longitudinal Associations of Semaglutide With Liver Fibrosis Score in People With HIV" by Jimmy Ma University of Washington, Seattle, WA, USA

Themed Discussion: Extra Large Challenges in Steatotic Liver Disease

"Discussion With Audience Questions and Answers" by

Themed Discussion: Machines, Models, and Messages

"Session Overview" by Ravi Goyal University of California San Diego, La Jolla, CA, USA

Themed Discussion: Machines, Models, and Messages

"Machine Learning and Longitudinal Data to Predict Unsuppressed HIV Viral Load in Rwanda, 2020-2025" by Ndinda Christian Rwanda Biomedical Centre, Kigali, Rwanda

Themed Discussion: Machines, Models, and Messages

"Effect of Machine-Learning-Guided Previsit Outreach to Patients at High Risk to Miss HIV Visits" by Joseph W. Hogan Brown University, Providence, RI, USA

Themed Discussion: Machines, Models, and Messages

"Sentiment Analysis of WhatsApp Messages to Identify Unrecognized HIV Prevention Needs in Kenya" by Jessica Haberer Massachusetts General Hospital, Boston, MA, USA

Themed Discussion: Machines, Models, and Messages

"Measuring Provider Quality of Care in Tanzania Using Large Language Models" by Alaa Abdellatif University of California San Francisco, San Francisco, CA, USA

Themed Discussion: Machines, Models, and Messages

"Discussion With Audience Questions and Answers" by

Themed Discussion: Precision Comes to Public Health

"Session Overview" by Suzue Saito ICAP at Columbia University, New York, NY, USA

Themed Discussion: Precision Comes to Public Health

"Quantifying Uncertainty in HIV Transmission Risk From Persons With Low-Level Viremia" by Michael Martin The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA

Themed Discussion: Precision Comes to Public Health

"Network Bridges to Predict Emerging HIV Transmission Hotspots in North Carolina" by Ann Dennis University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Themed Discussion: Precision Comes to Public Health

"Mapping Recent HIV Infections Among MSM in Thailand: Data-Driven Insights for Targeted Prevention" by Michael Reid

Themed Discussion: Precision Comes to Public Health

"Progress Towards HIV Epidemic Control Among Young Key Populations in India" by Eshan U. Patel The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA

Themed Discussion: Precision Comes to Public Health

"Discussion With Audience Questions and Answers" by

Themed Discussion: Targeting the HIV Reservoir: Novel Cure Strategies

"Session Overview" by Marina Caskey The Rockefeller University, New York, NY, USA

Themed Discussion: Targeting the HIV Reservoir: Novel Cure Strategies

"Targeting the HIV-1 Latent Reservoir With Tat-CRISPR Lipid Nanoparticles" by Keely Gliwa University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Themed Discussion: Targeting the HIV Reservoir: Novel Cure Strategies

"Bispecific Biologics That Activate Latent HIV-1 Ex Vivo and In Vivo" by David D. Ho Aaron Diamond AIDS Research Center, New York, NY, USA

Themed Discussion: Targeting the HIV Reservoir: Novel Cure Strategies

"Combination Therapy With Tat mRNA and a TLR9 Agonist Delays Post-ATI Rebound in the NHP Model" by Takuto Nogimori National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan

Themed Discussion: Targeting the HIV Reservoir: Novel Cure Strategies

"Markedly Reduced Mutability of Networked Epitopes Promotes CTL Clearance of the Latent HIV Reservoir" by Fernando B. Senjobe Harvard Medical School, Boston, MA, USA

Themed Discussion: Targeting the HIV Reservoir: Novel Cure Strategies

"Discussion With Audience Questions and Answers" by

Themed Discussion: Advancing Mental Health for Youth With HIV

"Session Overview" by Claude A. Mellins Columbia University Irving Medical Center, New York, NY, USA

Themed Discussion: Advancing Mental Health for Youth With HIV

"Depression, Anxiety, and Viral Suppression Among Adolescents and Young Adults in 9 African Countries" by Jiayu Wang University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Themed Discussion: Advancing Mental Health for Youth With HIV

"Implementation of a Mental Health Intervention for Youth With HIV in Kenya" by Pamela Kohler University of Washington, Seattle, WA, USA

Themed Discussion: Advancing Mental Health for Youth With HIV

"Primary Outcomes of SYV (Voice of Youth) Mental Health Intervention: A Randomized Trial in Tanzania" by Dorothy Dow Duke University Medical Center, Durham, NC, USA

Themed Discussion: Advancing Mental Health for Youth With HIV

"Primary Findings of IMPAACT 2016: A RCT of a Youth-Led Mental Health Intervention for Youth With HIV" by Geri Donenberg University of Illinois at Chicago Center for Dissemination and Implementation Science, Chicago, IL, USA

Themed Discussion: Advancing Mental Health for Youth With HIV

"Discussion With Audience Questions and Answers" by

Themed Discussion: Harnessing B-Cells and Antibodies for HIV Control

"Session Overview" by Nicole A. Doria-Rose Vaccine Research Center, Bethesda, MD, USA

Themed Discussion: Harnessing B-Cells and Antibodies for HIV Control

"AAV-Delivered Antibody Reaches Mucosal Sites and Protects Against SHIV Infection in Rhesus Macaques" by Luanna E. L. Vidal University of Miami, Miami, FL, USA

Themed Discussion: Harnessing B-Cells and Antibodies for HIV Control

"Beating the Clock: Timing 10E8.4/iMab Administration to Block SHIV Infection" by Matthew S. Parsons Armed Forces Research Institute of Medical Sciences in Bangkok, Bangkok, Thailand

Themed Discussion: Harnessing B-Cells and Antibodies for HIV Control

"Antigen-Specific Memory B Cells of Extrafollicular Origin May Contribute to ART-Free HIV Control" by Elif Cakan Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA

Themed Discussion: Harnessing B-Cells and Antibodies for HIV Control

"Evidence of Immune Activation During bNAb-Mediated HIV Suppression Following ATI" by Julia A. Wagner University of California San Francisco, San Francisco, CA, USA

Themed Discussion: Harnessing B-Cells and Antibodies for HIV Control

"Discussion With Audience Questions and Answers" by

Themed Discussion: Some Assembly Required: Self-Blood Collection and Testing

"Session Overview" by Michelle Rodolph World Health Organization, Geneva, Switzerland

Themed Discussion: Some Assembly Required: Self-Blood Collection and Testing

"Identifying Where HIV Self-Screening Has Greatest Impact: Analysis of Routine Data in South Africa" by Alexandra de Nooy Amsterdam Institute for Global Health and Development, Amsterdam, Netherlands

Themed Discussion: Some Assembly Required: Self-Blood Collection and Testing

"HIV Self-Testing by Motorcycle-Taxi Drivers: A Novel Approach for Case Detection in Kampala, Uganda" by Edith Namulema Mengo Hospital, Kampala, Uganda

Themed Discussion: Some Assembly Required: Self-Blood Collection and Testing

"Virtual Submission of HIV Viral Load in EPI-LoVE, a Digital Cohort of People Living With HIV in US" by Pamina M. Gorbach University of California Los Angeles, Los Angeles, CA, USA

Themed Discussion: Some Assembly Required: Self-Blood Collection and Testing

"Vending Machines as Stigma-Free Access Points for HIV/Syphilis Testing and Condoms" by David Closs Friends for All, Memphis, TN, USA

Themed Discussion: Some Assembly Required: Self-Blood Collection and Testing

"Discussion With Audience Questions and Answers" by

Themed Discussion: Tuberculosis: Innovative Screening and Diagnostic Approaches

"Session Overview" by Yukari C. Manabe The Johns Hopkins University School of Medicine, Baltimore, MD, USA

Themed Discussion: Tuberculosis: Innovative Screening and Diagnostic Approaches

"Efficiency of Portable Chest X-Ray Compared to Symptom-Based TB Screening in Southwest Nigeria" by Aderonke V. Agbaje Institute of Human Virology Nigeria, Abuja, Nigeria

Themed Discussion: Tuberculosis: Innovative Screening and Diagnostic Approaches

"High Prevalence of Asymptomatic Tuberculosis in an African Cohort of People With HIV (CoVPN 3008-TB)" by Asa Tapley University of Washington, Seattle, WA, USA

Themed Discussion: Tuberculosis: Innovative Screening and Diagnostic Approaches

"The Case for Routine Testing and Empiric Treatment of TB Meningitis in High HIV-Prevalence Settings" by James Milburn Botswana Harvard AIDS Institute Partnership, Gabarone, Botswana

Themed Discussion: Tuberculosis: Innovative Screening and Diagnostic Approaches

"Very Promising New Urinary LAM Assay for Tuberculosis Diagnosis in Children" by Adeline Riondel French National Institute of Health and Medical Research (Inserm), Paris, France

Themed Discussion: Tuberculosis: Innovative Screening and Diagnostic Approaches

"Discussion With Audience Questions and Answers" by